Extended-time period animal research have not been carried out to evaluate the carcinogenic prospective of codeine or of promethazine, nor are there other animal or human information about carcinogenicity, mutagenicity, or impairment of fertility with these brokers.
When the affected individual develops these signals or indications, raise the dose to the former level and taper additional gradually, possibly by escalating the interval amongst decreases, decreasing the quantity of alter in dose, or equally.
Unresponsive Cough The dosage of Promethazine HCl and Codeine Phosphate Oral Resolution should not be increased if cough fails to respond; an unresponsive cough ought to be reevaluated in five times or faster for attainable fundamental pathology, for example overseas body or reduced respiratory tract ailment [see Dosage and Administration (2.3)].
This medication may possibly bring about hurt and Demise if it is taken by other adults, young children, or pets. It's important to eliminate the medication the moment you no more have to have it or it is actually expired. You can do this in two means:
This medication can dry up and thicken mucus as part of your lungs, which makes it tougher to breathe and apparent your lungs. To help reduce this influence, drink plenty of fluids Except if if not directed by your health practitioner.
This products could have inactive components, which might lead to allergic reactions or other troubles. Check with your pharmacist for more details.
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Advise patients to often use an accurate milliliter measuring gadget when measuring and administering Promethazine HCl and Codeine Phosphate Oral Option. Tell sufferers that a house teaspoon just isn't an exact measuring product and this sort of use could lead to overdosage and serious adverse reactions [see Overdosage (10)].
Labor or Shipping Opioids cross the placenta and will develop respiratory despair and psycho-physiologic consequences Promethazine codeine syrup in neonates. An opioid antagonist, which include naloxone, must be available for reversal of opioid-induced respiratory melancholy inside the neonate.
Never rise up or sit up rapidly, particularly if you're an older affected person. This lessens the potential risk of dizzy or fainting spells. Alcohol might interfere While using the outcome of this medication. Keep away from alcoholic drinks.
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Don't flush medicines down the bathroom or pour them right into a drain Unless of course instructed to do so. Properly discard this products when it really is expired or now not required. Talk to your pharmacist or neighborhood squander disposal organization.
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Marketing or giving away Promethazine Hydrochloride and Codeine Phosphate Oral Answer may possibly damage Other folks, and it is from the legislation. Tell your Health care service provider Should you have ever abused or been depending on alcohol, prescription medicines or street prescription drugs.